
Sirolimus – Eluting Biodegradable Polymer Stent System
“DES Re-discovered”
Abrax TM Sirolimus-Eluting Stent System is designed to perform successfully even in the
most demanding cases. The combination of Sirolimus’ antiproliferative action coupled
with Rontis’ biodegradable polymer and proven balloon catheter ensures effective
treatment of clinically difficult lesions with confidence. This essentially means that
patients who receive Abrax TMare a lot less likely to need another repeat procedure in the short term.
Biodegradable polymer
- PLGA
- Uniform and site-specific drug delivery
- Thin layer 5 μm
- Complete degradation following the drug release into 6 weeks
- Eliminating inflammation and stent thrombosis
Stent platform
- Carbon ionized surface for higher biocompatibility and reduced restenosis rateCarbon ionized surface for higher biocompatibility and reduced restenosis rate
- DATS Technology (Dual Anti-Thrombogenic Stent Technology)
- MSC Design (Multivariate Stent Cell )
This design offers generous access for ballooning and stenting hemodynamically prominent coronary side-branches in order to optimize intramyocardial blood flow to subendocardial and intramural microvasculature. - Intra-cellular “sinusoidal links”
- Open cell design ensures balance of radial strength and flexibility
- Enhanced radiopacity
- Optimal scaffolding as well as stent-to-wall apposition with superior acute gain
Balloon catheter platform
- Lower inflation pressuresLower inflation pressures
- Homogenizes stent expansion
- Hydrophilicity lowers friction optimizing deliverability
Sirolimus
- Suppresses neointimal growth without suppressing endothelialization
- Reduces in-stent restenosis
- Drug load 2.0μg/mm2


CLINICAL STUDY
Klinik fûr Herz und Kreislauferkrankungen, Munich (Germany)
2-vessel disease | 28.0% of patiens | |
3-vessel disease | 57.0% of patiens | |
Complex lesions | 69.0% | |
Diabetes | 30.0% | |
Death or M.I. | 4.5% | |
TLR | 6.7% | |
MACE | 11.2% | |
URGENT TVR | 0.0% |
TECHNICAL DATA
Abrax TM Sirolimus – Eluting Biodegradable Polymer Coronary Stent System
Mode of exchange: | Rx | |
Baloon material / characteristic: | modified polyamide / semi-compliant | |
Guidewire compatibility (max): | 0.014″ | |
Usable Catheter length: | 142 cm | |
Guiding Catheter compatibility (min) | 5F | |
Nomimal Pressure: | 9 atm | |
Rated Burst Pressure: | 16-18 atm | |
Coating: | Abluminal | |
Shelf life: | 18 months |
Stent Specifications
Material: | Carbonized SS alloy | |
Strut thickness: | 110 μm (average) | |
Metal / Artery Ratio: | 13-15% |
Polymer/Drug Specifications
Drug carrier polymer: | Biodegradable – PLGA | |
Polymer biodegradation period: | 6 weeks | |
Polymer thickness: | ca. 5μm | |
Drug: | Sirolimus | |
Drug loading: | 2.0μg/mm2 |

